Lea Michele - Rachel Berry in Glee (Fox)
Tina Fey - Liz Lemon in 30 Rock (Nbc)
Toni Collette - Tara Gregson in The United States of Tara (Showtime)
Julia Louis-Dreyfus - Christine Campbell in La complicata vita di Christine (Cbs)
Edie Falco - Jackie Peyton in Nurse Jackie (Showtime)
Amy Poehler - Leslie Knope in Parks and Recreation (Nbc)