“Pilot” - Two brothers witness their mother's paranormal death and are trained to fight by their father, who aims to hunt down the thing that killed his wife.
“Wendigo” - Sam and Dean follow the coordinates in their father's journal and land in Colorado, where they investigate the disappearance of several campers.
“Dead in the Water” - Sam and Dean follow the coordinates in their father's journal and land in Colorado, where they investigate the disappearance of several campers.
“Phantom Traveler” - On TransNational flight 2485, a man possessed by the spirit of the Phantom Traveler causes the plane to crash, leaving only five survivors.
“Bloody Mary” - Several high schoolers dare their friend to look into a mirror and repeat a chant, not knowing that this will unleash a series of mysterious murders.
“Skin” - Sam and Dean help Sam's old college buddy after he is accused of a murder he swears he didn't commit.
“Hook Man” - Sam and Dean help Sam's old college buddy after he is accused of a murder he swears he didn't commit.
“Bugs” - Sam and Dean investigate a town's history and find that a new housing development is being built on sacred Native American land.
“Home” - Sam is haunted by a vision of a woman trapped in the brothers' childhood home and convinces a reluctant Dean that they need to go back there.
“Asylum” - Sam and Dean investigate an abandoned sanitarium and discover the patients had revolted against the cruel punishments inflicted by the head doctor.
“Scarecrow” - Sam and Dean finally make contact with their father, but he tells them to stop looking for him and sends them on another ghost-hunting job.
“Faith” - While battling a demon, Dean is electrocuted, resulting in permanent damage to his heart and leaving him with only a couple of months to live.
“Route 666” - Dean is contacted by his first love, Cassie, a girl who asks him to come to Mississippi to investigate a string of racially motivated murders.
“Nightmare” - Sam has a premonition in which a man is killed, but the murder is made to look like a suicide.
“The Benders” - Sam and Dean head to Minnesota, where a young boy witnesses a man vanishing into thin air.
“Shadow” - While investigating a mysterious death in Chicago, Sam and Dean run into Meg, who is thrilled to see Sam again.
“Hell House” - Sam and Dean investigate a house haunted by the ghost of a man who killed his six daughters during the 1930s.
“Something Wicked” - Sam and Dean investigate a small town in Wisconsin where children are falling into comas for no apparent reason.
“Provenance” - A young husband and wife are killed in their home shortly after buying an antique painting of a family portrait from around 1910.
“Dead Man’s Blood” - After a vampire hunter who was John's mentor is murdered, Sam and Dean are surprised when John himself shows up to solve the case.
“Salvation” - After a vampire hunter who was John's mentor is murdered, Sam and Dean are surprised when John himself shows up to solve the case.
“Devil’s Trap” - On a mission to save their father from Meg, Sam and Dean seek help from an old family friend.