63F presents with a two week history of progressive weakness and dysphagia. There is no diurnal variation. On examination she has a violaceous rash over the eyelids and papules over the knuckles. Tone is normal. There is a proximal pattern of weakness bilaterally. Reflexes are normal. Which of the following investigations would give you a definitive diagnosis?

6 votes

A. Serum CK
 
0% / 0 votes
B. Anti dsDNA antibody testing
 
0% / 0 votes
C. MRI whole spine
 
0% / 0 votes
D. Muscle biopsy
 
83% / 5 votes
E. Acetylcholine receptor antibody testing
 
17% / 1 vote


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