A 35 year old woman presents with a band-like sensation around her abdomen, leg weakness and bladder dysfunction. On questioning she reveals that she had an episode around a year ago, where she experienced left eye pain and problems with her vision, this resolved within a few weeks and she did not seek medical attention. On examination she has increased tone in her legs, bilateral weakness and hyperreflexia. What is/are the key factor(s) required to make a diagnosis of multiple sclerosis?

13 votes
Dissemination in time and space of CNS lesions
 
92% / 12 votes
Raised inflammatory markers
 
0% / 0 votes
Young age and female gender
 
0% / 0 votes
Oligoclonal bands in CSF
 
8% / 1 vote
Family history of multiple sclerosis
 
0% / 0 votes


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