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63F presents with a two week history of progressive weakness and dysphagia. There is no diurnal variation. On examination she has a violaceous rash over the eyelids and papules over the knuckles. Tone is normal. Shoulder abduction is 1/5 bilaterally and finger extension 4/5. Hip flexion is 1/5 bilaterally and foot dorsiflexion and plantarflexion is 4/5. Given the likely diagnosis, what is the pattern of weakness and where would you localise the lesion to?
63F presents with a two week history of progressive weakness and dysphagia. There is no diurnal variation. On examination she has a violaceous rash over the eyelids and papules over the knuckles. Tone is normal. There is a proximal pattern of weakness bilaterally. Reflexes are normal. Which of the following investigations would give you a definitive diagnosis?
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